Immune system aging is a natural process in the body; During this period, the entire immune response undergoes restructuring. Immunologist and allergist Vladimir Polybok explained what this process affects.
“After 40-50 years, the release of new T lymphocytes from the thymus decreases, the diversity of the immune response narrows, and in older people, memory cells and exhausted cells accumulate, which are less able to recognize new infections and tumor antigens,” the expert noted in an interview with “ R.T.
According to the expert, restructuring does not begin immediately and has an impact on morbidity and mortality.
Polybok confirmed that changes in the immune system are noticeable after 60-65 years. In this era, cases of pneumonia and influenza are increasing, and complications of chronic diseases occur.
However, not everyone’s immune system ages in the same way. Polebock noted that there is a historical concept – the “immune elite”, and the expression applies to centenarians. These people retained their pool of naïve T cells longer than their peers.
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